Thirteen people had been arrested by midafternoon. Dozens of police officers in riot gear were standing nearby and quickly arrested one man. Others were arrested as several fistfights broke out.
This comes as thousands of other protesters gathered in cities across the country to pressure Trump to release his tax returns on Saturday which coincided with the deadline for U.S. tax filings.
Hundreds of President Trump supporters and anti-Trump protesters held dual demonstrations Saturday near the downtown area at 2151 Martin Luther King Jr. Way. The police seized numerous prohibited items, including sticks and knives, according to the agency.
In Washington, several thousand protesters of all ages gathered in front of the Capitol building housing Congress, holding signs such as "What is he hiding?" and "Real men pay their taxes". "You've earned your stripes, bro", A J Alegria, a 31-year-old Trump supporter who was among the injured in Berkeley, told the LA Times.
Pro-Trump and Anti-Trump groups met in the streets in Berkeley, California Saturday, descending into violence that swept across social media.
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Trump has said that Americans "don't care at all" about his tax returns, but polls show 74% of Americans say he should release them.
According to organizers, the clashes were independent of nationwide rallies protesting Trump's refusal to release his tax returns. As fist fights between people broke out there were cans and bottles throw between a barricade separating them, police ended up having to throw an explosive device at one point in hopes of regaining peace.
"They picked Berkeley because they want to feel they could do this in the most liberal place in the country", said Geoff Millard, an anti-Trump protester, Iraq war veteran and Mr San Francisco Leather 2017. He said the sign "means we're sick of living under neocon rule". The university said more than $100,000 in damage was done. "No one has applied for or obtained a permit for Saturday, and as a result, anyone at the park will be subject to these rules".
A bleeding right-wing protester records video of himself at the corner of Center and Milvia Streets in Berkeley, Calif. on Saturday, Apr. 15, 2017.
Organisers of "Tax March" in more than 150 cities across the country and beyond wanted to call attention to Trump's refusal to disclose his tax history, as his White House predecessors have done for more than 40 years.